進階生物藥學專題討論
Advanced Biopharmaceutical Sciences Seminar
學期
109-1
學分
0
學分
當期課號
B269
永久課號
A7784
開課單位
生物藥學研究所
授課教師
張牧新、蕭永基、蘇瑀、黃奇英、劉嘉仁、林蔚靖、翁芸芳
校區
陽明
類別
選修
上課時間表
| 節 | 週三 |
|---|---|
7 15:30–16:20 | 進階生物藥學專題討論 YC201（陽明） 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
概述
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先修科目
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備註
無備註
教學方式
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評分方式
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課程大綱
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週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 09/30(Wed) 施繼庭 Small-molecule MYC inhibitors suppress tumor growth and enhance immunotherapy Cancer Cell. 2019; 36: 483-497 |
| 第 2 週 | 10/07(Wed) Thi-Thu-Phuong Bui 彭裴氏 A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer Nature cell biology. 2019; 21:1413-1424 |
| 第 3 週 | 10/8 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Thu-Huyen Hoang 黃玉玄 Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. Molecular Medicine. 2020. |
| 第 4 週 | 10/14(Wed) Dr Une-Fang Ueng Xuan-Tung Ha 何春崧 Knockout of farnesoid X receptor aggravates process of diabetic cardiomyopathy |
| 第 5 週 | 10/15 (Thur) Dr. Huang, Dr. Chia-Jen Liu, Dr. Young-Ji Shiao Thi-Quynh-Trang Dao 莊氏瓊桃 HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease Nature Communication. 2020; 11:2484 |
| 第 6 週 | 10/21(Wed) Thi-Hong-Hanh Le 黎虹涵 Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension |
| 第 7 週 | 10/22 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Tri-Vien Le 袁治黎 Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC |
| 第 8 週 | 11/04(Wed) Midterm |
| 第 9 週 | 11/18(Wed) Thuc-Anh Nguyen 阮淑英 USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin Nature communication. 2019; 10:4184. |
| 第 10 週 | 11/25(Wed) Hien-Ly Doan 尹嫻璃 Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia Nature communication. 2019; 4869 |
| 第 11 週 | 11/26 (Thur) Dr. Huang and Dr. Chia-Jen Liu Huong Thi Nguyen NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism Nature Metabolism. 2019; 1:404-415 |
| 第 12 週 | 12/02(Wed) Thi-My-Trieu Tran 趙氏媚陳 Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway Nature. 2020; 10:5163 |
| 第 13 週 | 12/3 (Thur) Dr. Huang and Dr. Mu-Hsin Chang Trang Thi Huyen Nguyen Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1 Cell. 2019; 178(2): 316-329.e18 |
| 第 14 週 | 12/10 (Thur) Dr. Huang and Dr. Chia-Jen Liu My Nu Huyen Nguyen Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines Nature Biomedical engineering. 2020; 4: 636-648 |
| 第 15 週 | 12/16(Wed) 田婷怡 T cells with dysfunctional mitochondria induce multimorbidity and premature senescence. Science,2020 June 19; 368:1371–1376. |
| 第 16 週 | 12/23(Wed) 賴信宏 FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. Cell Stem Cell. 2019 Mar;24(3):447-461.e8. DOI: 10.1016/j.stem.2018.12.002. |
| 第 17 週 | 12/30(Wed) Final - |
| 第 18 週 | 彈性教學 |
教科書
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Office Hours
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