放射分子生物學
Radiation Molecular Biology
| 節 | 週三 |
|---|---|
7 15:30–16:20 | 放射分子生物學 YT103（陽明） 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
Based on molecular biology, this course will introduce the impact of ionizing radiation at the molecular level of cells and mammals, including DNA replication and recombination, DNA damage and repair, gene transcription and translation, regulation of gene expression, oxidative stress, radiation molecular biotechnology, molecular Information conduction and even system biology will be introduced and discussed. The topic of interestes include: 1. Ionizing radiation can cause biological damage, including inflammation, cell death, genetic effects, and cancer. 2. The triggering mechanism of these reactions includes a series of molecular-level actions and the conduction of molecular messages. 3. Ionizing radiation also causes damage to matter and its structure at the molecular level, resulting in macroscopic biological phenomena.
Suggested pre-course: Biochemistry
無備註
To offer the knowledge about the ionizing radiation may caused biological effects at the molecular levels, such as DNA replication , repair, gene transcription and translation, and even epigeneitc regulation etc.
期中考 (Midterm): 40% 期末考 (Final): 40% 出席率 (Attendence): 20%
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| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction of molecular biology and Radiation effects |
| 第 2 週 | Biochemical proterties of nucleic acid |
| 第 3 週 | DNA propagation |
| 第 4 週 | Radiation effects and Oxidative stress on gene regulation |
| 第 5 週 | Radiation effect on DNA – DNA damage and DNA Repair |
| 第 6 週 | Gene transcription |
| 第 7 週 | DNA recombination and gene transposition |
| 第 8 週 | 校際活動週 (放假一天) |
| 第 9 週 | Mid-term examination |
| 第 10 週 | Human Genome and single nucleotide polymorphisms (SNPs) |
| 第 11 週 | Regulation of gene transcription |
| 第 12 週 | Gene translation and Protein modification of Gene translation |
| 第 13 週 | RNA modification, editing and silencing |
| 第 14 週 | Molecular carcinogenesis by ionizing radiation |
| 第 15 週 | Principle of microarray and application and systems radiational biology |
| 第 16 週 | Final exam. |
| 第 17 週 | Current Topic for Radiation Molecular Biology (I) |
| 第 18 週 | Current Topic for Radiation Molecular Biology (II) |
Handouts provided by individual lecturers
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